Cerebral Vasospasm

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Cerebral Vasospasm

There are essentially two principal end points in cerebrosvascular regulation: maintenance of an adequate supply of blood and energy-yielding substra tes to the brain, despite the imposition of physiological or pathological stresses such as hypoxemia or reduced perfusion pressure, and precise and rapid coupling of regional cerebral bload flow (CBF) to changes in neuronal r equ i r emen t s 3 2 ...

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Cerebral arterial vasospasm.

A person in his 20s with known migraine with aura developed infarcts in the right middle cerebral artery and both anterior fields of supply (Figure 1 shows a magnetic tomography diffusion weighted series). Cerebral computed and magnetic tomography with magnetic resonance angiography (MRA) after admission showed normal blood flow and no sign of dissection or vasculitis. Hemicraniectomy became ne...

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Cerebral vasospasm with infarction.

Cerebral Vasospasm With Infarction • A case of intense unilateral cerebral vasospasm with appropriate neurological deficit following rupture of a posterior communicating aneurysm was followed with serial angiography. Associated with the initially intense spasm was subsequent regional hyperperfusion with early venous filling which disappeared as signs of focal cerebral atrophy ensued. These angi...

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Genetics of Cerebral Vasospasm

Cerebral vasospasm (CV) is a major source of morbidity and mortality in aneurysmal subarachnoid hemorrhage (aSAH). It is thought that an inflammatory cascade initiated by extravasated blood products precipitates CV, disrupting vascular smooth muscle cell function of major cerebral arteries, leading to vasoconstriction. Mechanisms of CV and modes of therapy are an active area of research. Unders...

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Reserpine and cerebral vasospasm.

Cerebral vasospasm was produced in the dog basilar artery by topically applied five-day-old clotted autologous blood, but not by freshly drawn blood. The spasm was reversed by methysergide, an antiserotonin agent. However, vasospasm was not produced by five-day-old clotted autologous blood from dogs pretreated with reserpine. This suggests platelet serotonin or a similar, unidentified substance...

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ژورنال

عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry

سال: 1981

ISSN: 0022-3050

DOI: 10.1136/jnnp.44.8.747-a